Chinese top seed Qiang Wang crashed out in round one of the Hua Hin Championships in Thailand.
Wang, the world number 45, was beaten by 7-5 3-6 6-4 by Russia's Ksenia Lykina.
Britain's Naomi Broady, seeded eighth, was also a first-round casualty after a 7-5 6-4 defeat to Ipek Soylu of Turkey.
Fourth seed Su-Wei Hsieh of Taipei is through, along with Austrian Barbara Haas, Czech Marie Bouzkova and Switzerland's Viktorija Golubic.
But seventh seed Misaki Doi of Japan tumbled out 6-4 6-2 to Russia's Irina Khromacheva.
At the Limoges Open in France, Monica Niculescu was a 6-3 7-5 winner over fellow Romanian Alexandra Dulgheru.
Home hope Manon Arcangioli lost 7-6 (7/1) 7-5 to Anhelina Kalinina of Ukraine while there were also wins for Basak Eraydin, Elena-Gabriela Ruse, Anna Blinkova and Antonia Lottner.